Monoclonal antibodies raised against a 4-nitrophenyl phosphonate hapten catalyze the stereospecific reduction of an .alpha.-ketoamide to the corresponding .alpha.-hydroxyamide in the presence of an appropriate reducing agent.
This invention lies in the field of the use of antibodies as catalysts in chemical reactions.
This invention was made with Government support under Contract No. DE-AC03-SF-00098 awarded by the Department of Energy. The Government has certain rights in this invention.