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DNA complexes with dyes designed for energy transfer as fluorescent markers

United States Patent

*** EXPIRED ***
5,646,264
July 8, 1997
View the Complete Patent at the US Patent & Trademark Office
Heteromultimeric fluorophores are provided for binding to DNA, which allow for the detection of DNA in electrical separations and preparation of probes having high-fluorescent efficiencies and large Stokes shifts. In addition, by appropriate choice of fluorescent molecules, one can use a single narrow wavelength band excitation light source, while obtaining fluorescent emissions having sufficient separation to be readily discriminated.
Glazer; Alexander N. (Orinda, CA), Benson; Scott C. (Albany, CA)
The Regents of the University of California (Oakland, CA)
08/ 340,749
January 23, 1995
CROSS-REFERENCE TO GOVERNMENT GRANT This invention was made with Government support under Grant Contract No. DE-FG-91ER61125 awarded by the Department of Energy. The Government has certain rights in this invention.