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Processes for producing polyhydroxybutyrate and related polyhydroxyalkanoates in the plastids of higher plants

United States Patent

5,610,041
March 11, 1997
View the Complete Patent at the US Patent & Trademark Office
The present invention relates to a process for producing poly-D-(-)-3-hydroxybutyric acid (PHB) and related polyhydroxyalkanoates (PHA) in the plastids of plants. The production of PHB is accomplished by genetically transforming plants with modified genes from microorganisms. The genes encode the enzymes required to synthesize PHB from acetyl-CoA or related metabolites and are fused with additional plant sequences for targeting the enzymes to the plastid.
Somerville; Christopher R. (Portola Valley, CA), Nawrath; Christiane (Palo Alto, CA), Poirier; Yves (Palo Alto, CA)
Board of Trustees operating Michigan State University (East Lansing, MI)
08/ 254,357
June 6, 1994
GOVERNMENT RIGHTS The invention described herein was made in the course of work under grant number DE-AC02-76ERO-1338 from the U.S. Department of Energy and No. DMB 9014037 from the National Science Foundation. The U.S. Government has certain rights under this invention.