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Microfluidic platform for multiplexed detection in single cells and methods thereof

United States Patent

9,957,554
May 1, 2018
View the Complete Patent at the US Patent & Trademark Office
Sandia National Laboratories - Visit the Intellectual Property Management and Licensing Website
The present invention relates to a microfluidic device and platform configured to conduct multiplexed analysis within the device. In particular, the device allows multiple targets to be detected on a single-cell level. Also provided are methods of performing multiplexed analyses to detect one or more target nucleic acids, proteins, and post-translational modifications.
Wu; Meiye (Tracy, CA), Singh; Anup K. (Daniville, CA)
National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM)
14/ 575,886
December 18, 2014
STATEMENT OF GOVERNMENT INTEREST This invention was made with Government support under contract no. DE-AC04-94AL85000 awarded by the U.S. Department of Energy to Sandia Corporation. The Government has certain rights in the invention.