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Apparatus, compositions, and methods for assessment of chronic obstructive pulmonary disease progression among rapid and slow decline conditions

United States Patent

9,885,085
February 6, 2018
View the Complete Patent at the US Patent & Trademark Office
Methods are disclosed for generating and isolating an informative content repository of respiratory related biomarkers to accurately determine whether an individual has normal or abnormal pulmonary function. Specifically, methods are directed to determination of whether individuals have chronic obstructive pulmonary disease, and if so, whether the affected individuals experience rapid long decline or slow lung decline as a result of COPD. Also disclosed is an informative content repository of chronic obstructive pulmonary disease biomarkers, which when linked with other informative content provides a powerful tool for diagnosis, study, therapeutic discovery and development, condition management, health maintenance, and linking chronic obstructive pulmonary disease through pattern of life style, environmental exposure, and genetic susceptibility and inheritance. Disclosed herein is a chronic obstructive pulmonary disease biomarker informative content repository comprising at least one COPD biomarker, apparatus and methods to diagnose, assess, address, and ameliorate related conditions.
Hoidal; John (Salt Lake City, UT), Scholand; Mary Beth (Salt Lake City, UT), Leppert; Mark F. (Salt Lake City, UT), Paul; Michael S. (Salt Lake City, UT), Gritz; Robert Mark (Fairfax, VA), Pounds; Joel Gardner (Richland, WA), Smith; Richard Dale (Richland, WA)
University of Utah Research Foundation (Salt Lake City, UT), Lineagen, Inc. (Salt Lake City, UT)
11/ 770,074
June 28, 2007
GOVERNMENTAL INSPECTION The present disclosure is subject to a right of inspection by the Department of Energy.