Skip to Content
Find More Like This
Return to Search

Cells and methods for producing fatty alcohols

United States Patent

July 18, 2017
View the Complete Patent at the US Patent & Trademark Office
Recombinant cells and methods for improved yield of fatty alcohols. The recombinant cells harbor a recombinant thioesterase gene, a recombinant acyl-CoA synthetase gene, and a recombinant acyl-CoA reductase gene. In addition, a gene product from one or more of an acyl-CoA dehydrogenase gene, an enoyl-CoA hydratase gene, a 3-hydroxyacyl-CoA dehydrogenase gene, and a 3-ketoacyl-CoA thiolase gene in the recombinant cells is functionally deleted. Culturing the recombinant cells produces fatty alcohols at high yields.
Pfleger; Brian F. (Madison, WI), Youngquist; J. Tyler (Medina, OH)
14/ 509,408
October 8, 2014
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH This invention was made with government support under DE-FC02-07ER64494 awarded by the US Department of Energy. The government has certain rights in the invention.