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Fluid control structures in microfluidic devices

United States Patent

9,644,623
May 9, 2017
View the Complete Patent at the US Patent & Trademark Office
Methods and apparatus for implementing microfluidic analysis devices are provided. A monolithic elastomer membrane associated with an integrated pneumatic manifold allows the placement and actuation of a variety of fluid control structures, such as structures for pumping, isolating, mixing, routing, merging, splitting, preparing, and storing volumes of fluid. The fluid control structures can be used to implement a variety of sample introduction, preparation, processing, and storage techniques.
Mathies; Richard A. (San Francisco, CA), Grover; William H. (Medford, MA), Skelley; Alison (Berkeley, CA), Lagally; Eric (Santa Barbara, CA), Liu; Chung N. (Albany, CA)
The Regents of the University of California (Oakland, CA)
12/ 782,598
20100224255
May 18, 2010
Statement Regarding Federally Sponsored Research This invention was made with government support under contract numbers DE-FG03-91ER61125 awarded by the U.S. Department of Energy and NAG5-9659 awarded by the National Aeronautics and Space Administration, and by grant numbers HG001399 and P01 CA077664 awarded by the National Institutes of Health. The government has certain rights in the invention.