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Compounds, compositions, pharmaceutical compositions, and methods of use

United States Patent

9,492,428
November 15, 2016
View the Complete Patent at the US Patent & Trademark Office
Certain embodiments of the invention include compositions comprising a compound of Formula (I), and salts, isomers, and derivatives thereof. Pharmaceutical compositions of some embodiments of the present invention comprise a compound of Formula (I), and salts, isomers, and derivatives thereof. Other embodiments of this invention include methods for treating disease (e.g., cancer) and methods for administering a compound of Formula (I), and salts, isomers, and derivatives thereof.
Hammond; Gerald B. (Shelbyville, KY), Jin; Zhuang (West Palm Beach, FL), Bates; Paula J. (Louisville, KY), Reyes-Reyes; Elsa Merit (Prospect, KY), Vaisberg; Abraham (Lima, PE)
University of Louisville Research Foundation, Inc. (Louisville, KY)
14/ 358,731
20150025129
November 16, 2012
GOVERNMENT RIGHTS This invention was made with the following U.S. Government support: (a) grant number W81XWH-07-1-0299 awarded by U.S. Department of Defense Prostrate Cancer Research Program (PCRP) of the Office of the Congressionally Directed Medical Research Medical Research Program (CDMRP), (b) grant number W81XWH awarded by the Department of Defense from the Telemedicine and Advanced Technology Research Center of the US Army, (c) grant number DEFG02-08CH11538 awarded by the Department of Energy, and (d) grant number EPS-0447479 funded by NSF/EPSCoR to the Center for Regulatory and Environmental Analytical Metabolomics (CREAM) Mass Spectrometry Facility (University of Louisville). The Government has certain rights in this invention.