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DNA-cell conjugates

United States Patent

May 3, 2016
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
The present invention provides conjugates of DNA and cells by linking the DNA to a native functional group on the cell surface. The cells can be without cell walls or can have cell walls. The modified cells can be linked to a substrate surface and used in assay or bioreactors.
Hsiao; Shih-Chia (Oakland, CA), Francis; Matthew B. (Berkeley, CA), Bertozzi; Carolyn (Berkeley, CA), Mathies; Richard (Moraga, CA), Chandra; Ravi (Ellicot City, MD), Douglas; Erik (Oakland, CA), Twite; Amy (Berkeley, CA), Toriello; Nicholas (Redwood City, CA), Onoe; Hiroaki (Tokyo, JP)
The Regents of the University of California (Oakland, CA)
13/ 263,129
April 8, 2010
STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT This invention was made with Government support under Contract No. DE-AC02-05CH11231 awarded by the U.S. Department of Energy and supported by the Nanoscale Science, Engineering, and Technology (NSET) Program of the Department of Energy, and the Office of Science, Office of Basic Energy Sciences, under Grant Nos. HG003329 and R01 GM072700 awarded by the National Institutes of Health, and under a National Institutes of Health Molecular Biophysics Training Grant No. T32GM08295. The Government has certain rights in this invention.