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Apparatus and method for nanoflow liquid jet and serial femtosecond x-ray protein crystallography

United States Patent

March 1, 2016
View the Complete Patent at the US Patent & Trademark Office
SLAC National Accelerator Laboratory - Visit the Technology Transfer Website
Techniques for nanoflow serial femtosecond x-ray protein crystallography include providing a sample fluid by mixing a plurality of a first target of interest with a carrier fluid and injecting the sample fluid into a vacuum chamber at a rate less than about 4 microliters per minute. In some embodiments, the carrier fluid has a viscosity greater than about 3 centipoise.
Bogan; Michael J. (San Francisco, CA), Laksmono; Hartawan (Sunnyvale, CA), Sierra; Raymond G. (Stanford, CA)
The Board of Trustees of the Leland Stanford Junior University (Palo Alto, CA)
13/ 896,303
May 16, 2013
STATEMENT OF GOVERNMENTAL INTEREST This invention was made with Government support under contract DE-AC02-76SF00515 awarded by the Department of Energy. The Government has certain rights in the invention.