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Ketol-acid reductoisomerase enzymes and methods of use

United States Patent

October 27, 2015
View the Complete Patent at the US Patent & Trademark Office
Provided herein are polypeptides having ketol-aid reductoisomerase activity as well as microbial host cells comprising such polypeptides. Polypeptides provided herein may be used in biosynthetic pathways, including, but not limited to, isobutanol biosynthetic pathways.
Govindarajan; Sridhar (Los Altos, CA), Li; Yougen (Pennington, NJ), Liao; Der-Ing (Wilmington, DE), O'Keefe; Daniel P. (Ridley Park, PA), Minshull; Jeremy Stephen (Los Altos, CA), Rothman; Steven Cary (Wilminton, DE), Tobias; Alexander Vincent (Hockessin, DE)
Butamax Advanced Biofuels LLC (Wilmington, DE)
13/ 891,963
May 10, 2013
GOVERNMENT LICENSE RIGHTS This invention was made with Government support under Agreement DE-AR0000006 awarded by the United States Department of Energy. The Government has certain rights in this invention.