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Systems and methods for laser assisted sample transfer to solution for chemical analysis

United States Patent

September 29, 2015
View the Complete Patent at the US Patent & Trademark Office
Oak Ridge National Laboratory - Visit the Partnerships Directorate Website
Systems and methods are described for laser ablation of an analyte from a specimen and capturing of the analyte in a dispensed solvent to form a testing solution. A solvent dispensing and extraction system can form a liquid microjunction with the specimen. The solvent dispensing and extraction system can include a surface sampling probe. The laser beam can be directed through the surface sampling probe. The surface sampling probe can also serve as an atomic force microscopy probe. The surface sampling probe can form a seal with the specimen. The testing solution including the analyte can then be analyzed using an analytical instrument or undergo further processing.
Van Berkel; Gary J. (Oak Ridge, TN), Kertesz; Vilmos (Knoxville, TN), Ovchinnikova; Olga S. (Knoxville, TN)
UT-Battelle, LLC (Oak Ridge, TN), University of Tennessee Research Foundation (Knoxville, TN)
14/ 267,482
May 1, 2014
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH This invention was made with government support under Contract No. DE-ACO5-00OR22725 awarded by the U.S. Department of Energy. The government has certain rights in this invention.