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Methods for isolation and viability assessment of biological organisms

United States Patent

February 3, 2015
View the Complete Patent at the US Patent & Trademark Office
Lawrence Livermore National Laboratory - Visit the Industrial Partnerships Office Website
Isolation of biological or chemical organisms can be accomplished using a surface enhanced Raman scattering (SERS) system. The SERS system can be a single or a stacked plurality of photonic crystal membranes with noble-metal lined through pores for flowing analyte potentially containing the biological or chemical organisms. The through pores can be adapted to trap individual biological or chemical organisms and emit SERS spectra, which can then be detected by a detector and further analyzed for viability of the biological or chemical organism.
Letant; Sonia Edith (Livermore, CA), Baker; Sarah Elyse (Pleasanton, CA), Bond; Tiziana (Livermore, CA), Chang; Allan Shih-Ping (San Ramon, CA)
Lawrence Livermore National Security, LLC (Livermore, CA)
13/ 117,079
May 26, 2011
STATEMENT OF GOVERNMENT GRANT The United States Government has rights in this invention pursuant to Contract No. DE-AC52-07NA27344 between the United States Department of Energy and Lawrence Livermore National Security, LLC for the operation of Lawrence Livermore National Laboratory.