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Microorganisms having enhanced resistance to acetate and methods of use

United States Patent

October 21, 2014
View the Complete Patent at the US Patent & Trademark Office
Oak Ridge National Laboratory - Visit the Partnerships Directorate Website
The present invention provides isolated or genetically modified strains of microorganisms that display enhanced resistance to acetate as a result of increased expression of a sodium proton antiporter. The present invention also provides methods for producing such microbial strains, as well as related promoter sequences and expression vectors. Further, the present invention provides methods of producing alcohol from biomass materials by using microorganisms with enhanced resistance to acetate.
Brown; Steven D. (Knoxville, TN), Yang; Shihui (Knoxville, TN)
UT-Batelle, LLC (Oakridge, TN)
13/ 688,636
November 29, 2012
This invention was made with government support under Contract Number DE-ACO5-000R22725 between the United States Department of Energy and UT-Battelle, LLC. The U.S. Government has certain rights in this invention.