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Nucleic acids encoding mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens

United States Patent

April 21, 2015
View the Complete Patent at the US Patent & Trademark Office
Los Alamos National Laboratory - Visit the Technology Transfer Division Website
The present invention relates to nucleic acids encoding mosaic clade M HIV-1 Env polypeptides and to compositions and vectors comprising same. The nucleic acids of the invention are suitable for use in inducing an immune response to HIV-1 in a human.
Korber; Bette T. (Los Alamos, NM), Fischer; William (Los Alamos, NM), Liao; Hua-Xin (Durham, NC), Haynes; Barton F. (Durham, NC), Letvin; Norman (Boston, MA), Hahn; Beatrice H. (Birmingham, AL)
Los Alamos National Security, LLC (Los Alamos, NM), Duke University (Durham, NC), Beth Israel Deaconess Medical Center (Boston, MA), The University of Alabama at Birmingham Research Foundation (Birmingham, AL)
13/ 094,734
April 26, 2011
This invention was made with Government support under Contract No. DE-AC52-06NA25396 awarded by the U.S. Department of Energy. The Government has certain rights in the invention.