Sieve valves for use in microfluidic device are provided. The valves are useful for impeding the flow of particles, such as chromatography beads or cells, in a microfluidic channel while allowing liquid solution to pass through the valve. The valves find particular use in making microfluidic chromatography modules.
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH
This invention was made with government support under Grant No. CA119347 awarded by the National Institutes of Health and Grant No. DE-FC02-02ER63420 awarded by the US Department of Energy. The government has certain rights in the invention