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Genetic barcodes

United States Patent

August 4, 2015
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
Herein are described multicolor FISH probe sets termed "genetic barcodes" targeting several cancer or disease-related loci to assess gene rearrangements and copy number changes in tumor cells. Two, three or more different fluorophores are used to detect the genetic barcode sections thus permitting unique labeling and multilocus analysis in individual cell nuclei. Gene specific barcodes can be generated and combined to provide both numerical and structural genetic information for these and other pertinent disease associated genes.
Weier; Heinz-Ulrich G. (El Cerrito, CA)
The Regents of the University of California (Oakland, CA)
13/ 849,452
March 22, 2013
STATEMENT OF GOVERNMENTAL SUPPORT This invention was made with government support under Contract No. DE-AC02-05CH11231 awarded by the U.S. Department of Energy and under Grant Numbers CA123370A and CA132815A awarded by the National Cancer Institute and the National Institutes of Health. The government has certain rights in the invention.