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Conformable actively multiplexed high-density surface electrode array for brain interfacing

United States Patent

January 13, 2015
View the Complete Patent at the US Patent & Trademark Office
Provided are methods and devices for interfacing with brain tissue, specifically for monitoring and/or actuation of spatio-temporal electrical waveforms. The device is conformable having a high electrode density and high spatial and temporal resolution. A conformable substrate supports a conformable electronic circuit and a barrier layer. Electrodes are positioned to provide electrical contact with a brain tissue. A controller monitors or actuates the electrodes, thereby interfacing with the brain tissue. In an aspect, methods are provided to monitor or actuate spatio-temporal electrical waveform over large brain surface areas by any of the devices disclosed herein.
Rogers; John (Champaign, IL), Kim; Dae-Hyeong (Champaign, IL), Litt; Brian (Bala Cynwyd, PA), Viventi; Jonathan (Philadelphia, PA)
The Board of Trustees of the University of Illinois (Urbana, IL), The Trustees of the University of Pennsylvania (Philadelphia, PA)
13/ 486,726
June 1, 2012
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT This invention was made with government support under DMI-0328162 awarded by the National Science Foundation, DE-FG02-07ER46471 awarded by the U.S. Department of Energy, NINDS RO1-NS041811, NINDS R01 NS 48598 and 2T32HL007954 awarded by the National Institutes of Health. The government has certain rights in the invention.