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Alteration and modulation of protein activity by varying post-translational modification

United States Patent

March 3, 2015
View the Complete Patent at the US Patent & Trademark Office
Idaho National Laboratory - Visit the Technology Transfer and Commercialization Office Website
Embodiments of the invention include methods of altering the enzymatic activity or solubility of an extremophilic enzyme or post-translationally modifying a protein of interest via using isolated or partially purified glycosyltransferases and/or post-translational modification proteins, extracts of cells comprising glycosyltransferases and/or post-translational modification proteins, and/or in cells comprising one or more glycosyltransferases and/or post-translational modification proteins.
Thompson; David N. (Idaho Falls, ID), Reed; David W. (Idaho Falls, ID), Thompson; Vicki S. (Idaho Falls, ID), Lacey; Jeffrey A. (Idaho Falls, ID), Apel; William A. (Jackson, WY)
Battelle Energy Alliance, LLC (Idaho Falls, ID)
12/ 655,993
January 12, 2010
GOVERNMENT RIGHTS This invention was made with government support under Contract Numbers DE-AC07-99ID13727 and DE-AC07-05ID14517 awarded by the United States Department of Energy. The government has certain rights in the invention.