The present disclosure provides a photoreactive synthetic regulator of protein function. The present disclosure further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present disclosure further provides methods of modulating protein function, involving use of light.
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH
This invention was made with government support under Grant No. 1PN2-EY018241 awarded by the National Institutes of Health, Grant No. CHE 0724212 awarded by the National Science Foundation, and Contract DE-AC02-05CH11231 awarded by the U.S. Department of Energy. The government has certain rights in the invention.