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Xylose utilization in recombinant Zymomonas

United States Patent

January 7, 2014
View the Complete Patent at the US Patent & Trademark Office
Zymomonas expressing xylose isomerase from A. missouriensis was found to have improved xylose utilization, growth, and ethanol production when grown in media containing xylose. Xylose isomerases related to that of A. missouriensis were identified structurally through molecular phylogenetic and Profile Hidden Markov Model analyses, providing xylose isomerases that may be used to improve xylose utilization.
Kahsay; Robel Y. (Wilmington, DE), Qi; Min (Hockessin, DE), Tao; Luan (Wallingford, PA), Viitanen; Paul V. (West Chester, PA), Yang; Jianjun (Hockessin, DE)
E I du Pont de Nemours and Company (Wilmington, DE)
13/ 161,749
June 16, 2011
STATEMENT OF GOVERNMENT RIGHTS This invention was made with United States government support under Contract Nos. DE-FC36-07GO17056 awarded by the Department of Energy. The government has certain rights in this invention.