The present invention provides rotenone analogs and methods of making and using them. Labeled with single photon and positron emitting isotopes, the rotenone analogs of the present invention are useful in, for example, clinical imaging applications as tracers to measure cardiac blood flow and detect regions of ischemia.
STATEMENT OF GOVERNMENTAL SUPPORT
This invention was made with government support under Grant (Contract) No. DE-AC03-76F00098 awarded by The United States Department of Energy and Grant No. 5R01EB000482-03 awarded by The United States Department of Health and Human Services. The government has certain rights to this invention.