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Microbial reductive dehalogenation of vinyl chloride

United States Patent

8,647,824
February 11, 2014
View the Complete Patent at the US Patent & Trademark Office
Compositions and methods are provided that relate to the bioremediation of chlorinated ethenes, particularly the bioremediation of vinyl chloride by Dehalococcoides-like organisms. An isolated strain of bacteria, Dehalococcoides sp. strain VS, that metabolizes vinyl chloride is provided; the genetic sequence of the enzyme responsible for vinyl chloride dehalogenation; methods of assessing the capability of endogenous organisms at an environmental site to metabolize vinyl chloride; and a method of using the strains of the invention for bioremediation.
Spormann; Alfred M. (Stanford, CA), Muller; Jochen A. (Baltimore, MD), Rosner; Bettina M. (Berlin, DE), Von Abendroth; Gregory (Mannheim, DE), Meshulam-Simon; Galit (Los Altos, CA), McCarty; Perry L. (Stanford, CA)
The Board of Trustees of the Leland Stanford Junior University (Palo Alto, CA)
13/ 294,927
20120082983
November 11, 2011
GOVERNMENT LICENSE RIGHTS This invention was made with Government support under Government Grant DACA72-00-C-0010, awarded by the Department of the Army; DE-FG07-99ER62883, awarded by the Department of Energy; and 825689016 awarded by the Environmental Protection Agency. The Government has certain rights in this invention.