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Transcription factor-based biosensor

United States Patent

October 8, 2013
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
The present invention provides for a system comprising a BmoR transcription factor, a .sigma..sup.54-RNA polymerase, and a pBMO promoter operatively linked to a reporter gene, wherein the pBMO promoter is capable of expression of the reporter gene with an activated form of the BmoR and the .sigma..sup.54-RNA polymerase.
Dietrich; Jeffrey A. (San Francisco, CA), Keasling; Jay D. (Berkeley, CA)
The Regents of the University of California (Oakland, CA)
12/ 767,649
April 26, 2010
STATEMENT OF GOVERNMENTAL SUPPORT The invention described and claimed herein was made in part utilizing funds supplied by the U.S. Department of Energy under Contract No. DE-AC02-05CH11231 and NIH Grant No. GM008352. The government has certain rights in this invention.