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Xylose utilization in recombinant zymomonas

United States Patent

March 25, 2014
View the Complete Patent at the US Patent & Trademark Office
Xylose-utilizing Zymomonas strains studied were found to accumulate ribulose when grown in xylose-containing media. Engineering these strains to increase ribose-5-phosphate isomerase activity led to reduced ribulose accumulation, improved growth, improved xylose utilization, and increased ethanol production.
Caimi; Perry G. (Kennett Square, PA), McCole; Laura (East Fallowfield, PA), Tao; Luan (Wallingford, PA), Tomb; Jean-Francois (Wilmington, DE), Viitanen; Paul V. (West Chester, PA)
E I du Pont de Nemours and Company (Wilmington, DE)
13/ 161,734
June 16, 2011
STATEMENT OF GOVERNMENT RIGHTS This invention was made with United States government support under Contract Nos. DE-FC36-07GO17056 awarded by the Department of Energy. The government has certain rights in this invention.