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Cellulase variants with improved expression, activity and stability, and use thereof

United States Patent

March 25, 2014
View the Complete Patent at the US Patent & Trademark Office
The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
Aehle; Wolfgang (Zwingenberg, DE), Bott; Richard R. (Burlingame, CA), Bower; Benjamin (Newark, CA), Caspi; Jonathan (Sunnyvale, CA), Estell; David A. (San Francisco, CA), Goedegebuur; Frits (Vlaardingen, NL), Hommes; Ronaldus W. J. (Haarlem, NL), Kaper; Thijs (Half Moon Bay, CA), Kelemen; Bradley (Menlo Park, CA), Kralj; Slavko (Oegstgeest, NL), Van Lieshout; Johan (Utrecht, NL), Nikolaev; Igor (Noordwijk, NL), Van Stigt Thans; Sander (Zevenbergen, NL), Wallace; Louise (Palo Alto, CA), Vogtentanz; Gudrun (Sunnyvale, CA), Sandgren; Mats (Uppsala, SE)
Danisco US Inc. (Palo Alto, CA)
13/ 321,928
June 3, 2010
STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT This invention was made with Government support under conditional award no: DE-FC36-08GO18078 awarded by the Department of Energy. The Government has certain rights in this invention.