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Cellulases, nucleic acids encoding them and methods for making and using them

United States Patent

8,426,184
April 23, 2013
View the Complete Patent at the US Patent & Trademark Office
This invention relates to molecular and cellular biology and biochemistry. In one aspect, the invention provides polypeptides having cellulase activity, e.g., endoglucanase, cellobiohydrolase, mannanase and/or .beta.-glucosidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides cellulase activity, e.g., endoglucanase, cellobiohydrolase, mannanase and/or .beta.-glucosidase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural, food and feed processing and industrial contexts.
Blum; David (Nashville, TN), Gemsch Cuenca; Joslin (San Diego, CA), Dycaico; Mark (San Diego, CA)
BP Corporation North America (Houston, TX), Verenium Corporation (San Diego, CA)
11/ 908,672
20100003234
January 13, 2006
GOVERNMENT SUPPORT This invention was made with United States Government support under Contract Nos. DE-FG03-02ER83395 and DE-FG02-03ER83865, awarded by the Department of Energy. The Government has certain rights in this invention.