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High temperature flow-through device for rapid solubilization and analysis

United States Patent

April 23, 2013
View the Complete Patent at the US Patent & Trademark Office
Sandia National Laboratories - Visit the Intellectual Property Management and Licensing Website
Devices and methods for thermally lysing of biological material, for example vegetative bacterial cells and bacterial spores, are provided. Hot solution methods for solubilizing bacterial spores are described. Systems for direct analysis are disclosed including thermal lysers coupled to sample preparation stations. Integrated systems capable of performing sample lysis, labeling and protein fingerprint analysis of biological material, for example, vegetative bacterial cells, bacterial spores and viruses are provided.
West; Jason A. A. (Pleasanton, CA), Hukari; Kyle W. (Dublin, CA), Patel; Kamlesh D. (Dublin, CA), Peterson; Kenneth A. (Albuquerque, NM), Renzi; Ronald F. (Tracy, CA)
Sandia National Laboratories (Livermore, CA)
13/ 308,228
November 30, 2011
STATEMENT OF GOVERNMENT INTEREST This invention was made with Government support under Government Contract No. DE-AC04-94AL85000 awarded by the U.S. Department of Energy to Sandia Corporation. The Government has certain rights in the invention, including a paid-up license and the right, in limited circumstances, to require the owner of any patent issuing in this invention to license others on reasonable terms.