Skip to Content
Find More Like This
Return to Search

High density growth of T7 expression strains with auto-induction option

United States Patent

March 19, 2013
View the Complete Patent at the US Patent & Trademark Office
Brookhaven National Laboratory - Visit the Office of Technology Commercialization and Partnerships Website
A method for promoting and suppressing auto-induction of transcription of a cloned gene 1 of bacteriophage T7 in cultures of bacterial cells grown batchwise is disclosed. The transcription is under the control of a promoter whose activity can be induced by an exogenous inducer whose ability to induce said promoter is dependent on the metabolic state of said bacterial cells.
Studier; F. William (Stony Brook, NY)
Brookhaven Science Associates, LLC (Upton, NY)
11/ 741,282
April 27, 2007
GOVERNMENT SUPPORT This invention was made with Government support under contract number DE-AC02-98CH10886, awarded by the U.S. Department of Energy. The Government has certain rights in the invention.