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L-arabinose fermenting yeast

United States Patent

February 12, 2013
View the Complete Patent at the US Patent & Trademark Office
National Renewable Energy Laboratory - Visit the NREL Technology Transfer Website
An L-arabinose utilizing yeast strain is provided for the production of ethanol by introducing and expressing bacterial araA, araB and araD genes. L-arabinose transporters are also introduced into the yeast to enhance the uptake of arabinose. The yeast carries additional genomic mutations enabling it to consume L-arabinose, even as the only carbon source, and to produce ethanol. A yeast strain engineered to metabolize arabinose through a novel pathway is also disclosed. Methods of producing ethanol include utilizing these modified yeast strains.
Zhang; Min (Lakewood, CO), Singh; Arjun (Lakewood, CO), Suominen; Pirkko (Minnetonka, MN), Knoshaug; Eric (Golden, CO), Franden; Mary Ann (Centennial, CO), Jarvis; Eric (Boulder, CO)
Alliance for Sustainable Energy, LLC (Golden, CO)
12/ 909,523
October 21, 2010
The United States Government has rights in this invention under Contract No. DE-AC36-99GO10337 between the United States Department of Energy and the National Renewable Energy Laboratory, a Division of the Midwest Research Institute.