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Multi-layer micro/nanofluid devices with bio-nanovalves

United States Patent

January 1, 2013
View the Complete Patent at the US Patent & Trademark Office
A user-friendly multi-layer micro/nanofluidic flow device and micro/nano fabrication process are provided for numerous uses. The multi-layer micro/nanofluidic flow device can comprise: a substrate, such as indium tin oxide coated glass (ITO glass); a conductive layer of ferroelectric material, preferably comprising a PZT layer of lead zirconate titanate (PZT) positioned on the substrate; electrodes connected to the conductive layer; a nanofluidics layer positioned on the conductive layer and defining nanochannels; a microfluidics layer positioned upon the nanofluidics layer and defining microchannels; and biomolecular nanovalves providing bio-nanovalves which are moveable from a closed position to an open position to control fluid flow at a nanoscale.
Li; Hao (Austin, TX), Ocola; Leonidas E. (Oswego, IL), Auciello; Orlando H. (Bolingbrook, IL), Firestone; Millicent A. (Elmhurst, IL)
UChicago Argonne, LLC (Argonne, IL)
12/ 391,486
February 24, 2009
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT The United States Government has rights in this invention pursuant to Contract No. LDRD 2006-269-NO and Contract No. DE-ACO2-06CH11357 between the U.S. Department of Energy (DOE) and UChicago Argonne, LLC representing Argonne National Laboratory.