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Microfluidic chemical reaction circuits

United States Patent

June 26, 2012
View the Complete Patent at the US Patent & Trademark Office
New microfluidic devices, useful for carrying out chemical reactions, are provided. The devices are adapted for on-chip solvent exchange, chemical processes requiring multiple chemical reactions, and rapid concentration of reagents.
Lee; Chung-cheng (Irvine, CA), Sui; Guodong (Los Angeles, CA), Elizarov; Arkadij (Valley Village, CA), Kolb; Hartmuth C. (Playa del Rey, CA), Huang; Jiang (San Jose, CA), Heath; James R. (South Pasadena, CA), Phelps; Michael E. (Los Angeles, CA), Quake; Stephen R. (Stanford, CA), Tseng; Hsian-rong (Los Angeles, CA), Wyatt; Paul (Tipperary, IE), Daridon; Antoine (Mont-Sur-Rolle, CH)
Fluidigm Corporation (So. San Francisco, CA), California Institute of Technology (Pasadena, CA), The Regents of the University of California (Oakland, CA), Siemens Medical Solutions USA, Inc. (Malvern, PA)
11/ 792,168
December 5, 2005
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH Work described herein has been supported, in part, by the Department of Energy (DOE grant no. DE-FC02-02ER63420-S-106,907) and the National Cancer Institute (5P50 CA086306). The United States Government may have certain rights in the invention.