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In vivo incorporation of unnatural amino acids

United States Patent

May 8, 2012
View the Complete Patent at the US Patent & Trademark Office
The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.
Schultz; Peter G. (La Jolla, CA), Wang; Lei (San Diego, CA), Anderson; John Christopher (San Diego, CA), Chin; Jason W. (Cambridge, GB), Liu; David R. (Lexington, MA), Magliery; Thomas J. (North Haven, CT), Meggers; Eric L. (Philadelphia, PA), Mehl; Ryan Aaron (Lancaster, PA), Pastrnak; Miro (San Diego, CA), Santoro; Stephen William (Cambridge, MA), Zhang; Zhiwen (San Diego, CA)
The Scripps Research Institute (La Jolla, CA), The Regents of the University of California (Oakland, CA)
11/ 978,156
October 26, 2007
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT The invention was made with United States Government support under Grant No. N0001498F0402 from the Office of Naval Research, Grant No. GM62159 from the National Institutes of Health, and Contract Nos. DE-FG03-00ER45812, DE-AC-3-76SF00098 from the Department of Energy. The United States Government has certain rights in the invention.