Patent Number: 8,119,140
Issued: February 21, 2012
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Los Alamos National Laboratory
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Abstract: The present invention relates to mosaic clade M HIV-1 Nef polypeptides and to compositions comprising same. The polypeptides of the invention are suitable for use in inducing an immune response to HIV-1 in a human.
Korber; Bette T. (Los Alamos, NM), Perkins; Simon (Los Alamos, NM), Bhattacharya; Tanmoy (Los Alamos, NM), Fischer; William M. (Los Alamos, NM), Theiler; James (Los Alamos, NM), Letvin; Norman (Boston, MA), Haynes; Barton F. (Durham, NC), Hahn; Beatrice H. (Birmingham, AL), Yusim; Karina (Los Alamos, NM), Kuiken; Carla (Los Alamos, NM)
Los Alamos Security, LLC (Los Alamos, NM), Beth Israel Deaconess Medical Center (Boston, MA), Duke University (Durham, NC), The University of Alabama at Birmingham Research Foundation (Birmingham, AL)
Application Number: 11/
Filed: August 23, 2006
Government Interests: This invention was made with Government support under Contract No. DE-AC52-06NA25396 awarded by the U.S. Department of Energy. The Government has certain rights in the invention.