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Immunogenic compositions comprising human immunodeficiency virus (HIV) mosaic Nef proteins

United States Patent

February 21, 2012
View the Complete Patent at the US Patent & Trademark Office
Los Alamos National Laboratory - Visit the Technology Transfer Division Website
The present invention relates to mosaic clade M HIV-1 Nef polypeptides and to compositions comprising same. The polypeptides of the invention are suitable for use in inducing an immune response to HIV-1 in a human.
Korber; Bette T. (Los Alamos, NM), Perkins; Simon (Los Alamos, NM), Bhattacharya; Tanmoy (Los Alamos, NM), Fischer; William M. (Los Alamos, NM), Theiler; James (Los Alamos, NM), Letvin; Norman (Boston, MA), Haynes; Barton F. (Durham, NC), Hahn; Beatrice H. (Birmingham, AL), Yusim; Karina (Los Alamos, NM), Kuiken; Carla (Los Alamos, NM)
Los Alamos Security, LLC (Los Alamos, NM), Beth Israel Deaconess Medical Center (Boston, MA), Duke University (Durham, NC), The University of Alabama at Birmingham Research Foundation (Birmingham, AL)
11/ 990,222
August 23, 2006
This invention was made with Government support under Contract No. DE-AC52-06NA25396 awarded by the U.S. Department of Energy. The Government has certain rights in the invention.