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Genetically modified yeast of the species Issatchenkia orientalis and closely relates species, and fermentation processes using same

United States Patent

January 17, 2012
View the Complete Patent at the US Patent & Trademark Office
Cells of the species Issatchenkia orientalis and closely related yeast species are transformed with a vector to introduce an exogenous lactate dehydrogenase gene. The cells produce lactic acid efficiently and are resistant at low pH, high lactate titer conditions.
Suominen; Pirkko (Maple Grove, MN), Aristidou; Aristos (Highland Ranch, CO), Pentilla; Merja (Helsinki, FI), Ilmen; Marja (Helsinki, FI), Ruohonen; Laura (Helsinki, FI), Koivuranta; Kari (Vantaa, FI), Roberg-Perez; Kevin (Minneapolis, MN)
Cargill Inc. (Wayzata, MN)
11/ 921,161
May 30, 2006
This invention was made under contract no. DE-FC07-021D14349 with the United States Department of Energy. The United States Government has certain rights to this invention.