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Exo-endo cellulase fusion protein

United States Patent

January 17, 2012
View the Complete Patent at the US Patent & Trademark Office
National Renewable Energy Laboratory - Visit the NREL Technology Transfer Website
The present invention relates to a heterologous exo-endo cellulase fusion construct, which encodes a fusion protein having cellulolytic activity comprising a catalytic domain derived from a fungal exo-cellobiohydrolase and a catalytic domain derived from an endoglucanase. The invention also relates to vectors and fungal host cells comprising the heterologous exo-endo cellulase fusion construct as well as methods for producing a cellulase fusion protein and enzymatic cellulase compositions.
Bower; Benjamin S. (Palo Alto, CA), Larenas; Edmund A. (Palo Alto, CA), Mitchinson; Colin (Palo Alto, CA)
Danisco US Inc. (Palo Alto, CA)
11/ 088,306
March 23, 2005
SPONSORED RESEARCH AND DEVELOPMENT Portions of this work were funded by Subcontract No. ZC0-0-30017-01 with the National Renewable Energy Laboratory under Prime Contract No. DE-AC36-99G010337 with the United States Department of Energy. Accordingly, the United States Government may have certain rights in the invention.