Skip to Content
Find More Like This
Return to Search

Self-assembly of peptide-amphiphile nanofibers under physiological conditions

United States Patent

November 22, 2011
View the Complete Patent at the US Patent & Trademark Office
The present invention provides a method of promoting neuron growth and development by contacting cells with a peptide amphiphile molecule in an aqueous solution in the presence of a metal ion. According to the method, the peptide amphiphile forms a cylindrical micellar nanofiber composed of beta-sheets, which promote neuron growth and development.
Stupp; Samuel I. (Chicago, IL), Hartgerink; Jeffrey D. (Pearland, TX), Beniash; Elia (Auburndale, MA)
Northwestern University (Evanston, IL)
12/ 797,586
June 9, 2010
This invention was made with government support under Grant Number DMR-9996253awarded by the National Science Foundation, and Grant Number F49620-00-1-0283/P01awarded by the Air Force Office of Scientific Research (MURI), and Grant Number DE-FG02-00ER45810 awarded by the Department of Energy. The government has certain rights in the invention.