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Monolithic multinozzle emitters for nanoelectrospray mass spectrometry

United States Patent

September 20, 2011
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
Novel and significantly simplified procedures for fabrication of fully integrated nanoelectrospray emitters have been described. For nanofabricated monolithic multinozzle emitters (NM.sup.2 emitters), a bottom up approach using silicon nanowires on a silicon sliver is used. For microfabricated monolithic multinozzle emitters (M.sup.3 emitters), a top down approach using MEMS techniques on silicon wafers is used. The emitters have performance comparable to that of commercially-available silica capillary emitters for nanoelectrospray mass spectrometry.
Wang; Daojing (Daly City, CA), Yang; Peidong (Kensington, CA), Kim; Woong (Seoul, KR), Fan; Rong (Pasadena, CA)
The Regents of the University of California (Oakland, CA)
12/ 298,905
October 28, 2008
STATEMENT OF GOVERNMENTAL SUPPORT The invention described and claimed herein was made in part utilizing funds supplied by the U.S. Department of Energy under Contract No. DE-AC02-05CH11231 and in part utilizing funds supplied by National Institutes of Health Grant R21GM077870. The U.S. Government has certain rights in this invention.