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Bioactivation of particles

United States Patent

August 16, 2011
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
Particles are bioactivated by attaching bioactivation peptides to the particle surface. The bioactivation peptides are peptide-based compounds that impart one or more biologically important functions to the particles. Each bioactivation peptide includes a molecular or surface recognition part that binds with the surface of the particle and one or more functional parts. The surface recognition part includes an amino-end and a carboxy-end and is composed of one or more hydrophobic spacers and one or more binding clusters. The functional part(s) is attached to the surface recognition part at the amino-end and/or said carboxy-end.
Pinaud; Fabien (Berkeley, CA), King; David (San Francisco, CA), Weiss; Shimon (Los Angeles, CA)
The Regents of the University of California (Oakland, CA)
10/ 513,567
May 7, 2003
This invention was made with Government support of Grant Nos. EB000312 and RR014891 awarded by the National Institutes of Health and Grant No. DE-AC03-76SF00098 awarded by the Department of Energy. The Government has certain rights in this invention.