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Magnetic nanotubes

United States Patent

November 16, 2010
View the Complete Patent at the US Patent & Trademark Office
A magnetic nanotube includes bacterial magnetic nanocrystals contacted onto a nanotube which absorbs the nanocrystals. The nanocrystals are contacted on at least one surface of the nanotube. A method of fabricating a magnetic nanotube includes synthesizing the bacterial magnetic nanocrystals, which have an outer layer of proteins. A nanotube provided is capable of absorbing the nanocrystals and contacting the nanotube with the nanocrystals. The nanotube is preferably a peptide bolaamphiphile. A nanotube solution and a nanocrystal solution including a buffer and a concentration of nanocrystals are mixed. The concentration of nanocrystals is optimized, resulting in a nanocrystal to nanotube ratio for which bacterial magnetic nanocrystals are immobilized on at least one surface of the nanotubes. The ratio controls whether the nanocrystals bind only to the interior or to the exterior surfaces of the nanotubes. Uses include cell manipulation and separation, biological assay, enzyme recovery, and biosensors.
Matsui; Hiroshi (Glen Rock, NJ), Matsunaga; Tadashi (Tokyo, JP)
Research Foundation of the City University of New York (New York, NY), National University Corporation of Tokyo University of Agriculture and Technology (Tokyo, JP), N/A (
10/ 593,514
March 14, 2005
This invention was made with support from the U.S. Government under Contract No. DE-FG-02-01ER45935 awarded by the Department of Energy. The U.S. Government has certain rights in the invention.