An analytical test for an analyte comprises (a) a base, having a reaction area and a visualization area, (b) a capture species, on the base in the visualization area, comprising nucleic acid, and (c) analysis chemistry reagents, on the base in the reaction area. The analysis chemistry reagents comprise (i) a substrate comprising nucleic acid and a first label, and (ii) a reactor comprising nucleic acid. The analysis chemistry reagents can react with a sample comprising the analyte and water, to produce a visualization species comprising nucleic acid and the first label, and the capture species can bind the visualization species.
FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT
The subject matter of this application may have been funded in part under the following research grants and contracts: Contract Numbers DMR-0117792 and CTS-0120978 awarded by the National Science Foundation, Contract Number DEFG02-01ER63179 awarded by United States Department of Energy, and Contract Number DAAD19-03-1-0227 awarded by the Department of Defense. The U.S. Government may certain have rights in this invention.