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High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography

United States Patent

September 7, 2010
View the Complete Patent at the US Patent & Trademark Office
Lawrence Livermore National Laboratory - Visit the Industrial Partnerships Office Website
This invention permits retinal images to be acquired at high speed and with unprecedented resolution in three dimensions (4.times.4.times.6 .mu.m). The instrument achieves high lateral resolution by using adaptive optics to correct optical aberrations of the human eye in real time. High axial resolution and high speed are made possible by the use of Fourier-domain optical coherence tomography. Using this system, we have demonstrated the ability to image microscopic blood vessels and the cone photoreceptor mosaic.
Olivier; Scot S. (Livermore, CA), Werner; John S. (Davis, CA), Zawadzki; Robert J. (Sacramento, CA), Laut; Sophie P. (Pasedena, CA), Jones; Steven M. (Livermore, CA)
Lawrence Livermore National Security, LLC (Livermore, CA), University of California (Oakland, CA)
11/ 417,074
May 2, 2006
The United States Government has rights in this invention pursuant to Contract No. W-7405ENG-48 between the United States Department of Energy and the University of California for the operation of Lawrence Livermore National Laboratory.