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PH dependent adhesive peptides

United States Patent

June 29, 2010
View the Complete Patent at the US Patent & Trademark Office
A novel peptide adhesive motif is described that requires no receptor or cross-links to achieve maximal adhesive strength. Several peptides with different degrees of adhesive strength have been designed and synthesized using solid phase chemistries. All peptides contain a common hydrophobic core sequence flanked by positively or negatively charged amino acids sequences.
Tomich; John (Manhattan, KS), Iwamoto; Takeo (Manhattan, KS), Shen; Xinchun (Chapel Hill, NC), Sun; Xiuzhi Susan (Manhattan, KS)
Kansas State University Research Foundation (Manhattan, KS)
11/ 793,187
December 16, 2005
STATEMENT OF GOVERNMENT SUPPORT Partial support for these studies was provided by US Department of Energy (Grant #DE5 FC07-01ID14217). The US Government, therefore, has certain rights in this invention.