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Flow cytometer acquisition and detection system

United States Patent

May 4, 2010
View the Complete Patent at the US Patent & Trademark Office
A flow cytometer has a flow cell through which a sample flows and at least one laser emitting an excitation beam for illuminating a corresponding interrogation region in the flow cell. Scattered and fluorescence light from each interrogation region is collected by one or more input fibers for that region, and the input fiber(s) are fed to a dispersion module for that interrogation region that disperses the incoming light into different spectral regions. The dispersed light is conveyed, such as by a plurality of output fibers, to one or more photosensitive detectors. Thus, time multiplexed light signals may be delivered to a detector whereby several unique light signals can be measured by a single detector.
Casstevens; Martin K. (Amherst, NY), Burzynski; Ryszard (Kenmore, NY), Weibel; John (Tonawanda, NY), Kachynski; Alexander (Amherst, NY)
Advanced Cytometry Instrumentation Systems, Inc. (Amherst, NY)
11/ 380,434
April 27, 2006
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH This work was supported by Grant No. DE-FG02-01ER83134 from the Department of Energy. The United States Government has certain rights in the invention.