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Photoswitchable method for the ordered attachment of proteins to surfaces

United States Patent

April 20, 2010
View the Complete Patent at the US Patent & Trademark Office
Lawrence Livermore National Laboratory - Visit the Industrial Partnerships Office Website
Described herein is a method for the attachment of proteins to any solid support with control over the orientation of the attachment. The method is extremely efficient, not requiring the previous purification of the protein to be attached, and can be activated by UV-light. Spatially addressable arrays of multiple protein components can be generated by using standard photolithographic techniques.
Camarero; Julio A. (Livermore, CA), De Yoreo; James J. (Clayton, CA), Kwon; Youngeun (Livermore, CA)
Lawrence Livermore National Security, LLC (Livermore, CA)
11/ 688,171
March 19, 2007
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH The United States Government has rights in this invention pursuant to Contract No. W-7405-ENG-48 between the United States Department of Energy and the University of California for the operation of Lawrence Livermore National Laboratory.