Skip to Content
Find More Like This
Return to Search

Rapid classification of biological components

United States Patent

March 23, 2010
View the Complete Patent at the US Patent & Trademark Office
Idaho National Laboratory - Visit the Technology Transfer and Commercialization Office Website
A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, Cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens of the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.
Thompson; Vicki S. (Idaho Falls, ID), Barrett; Karen B. (Meridian, ID), Key; Diane E. (Idaho Falls, ID)
Battelle Energy Alliance, LLC (Idaho Falls, ID)
11/ 101,254
April 6, 2005
CONTRACTUAL ORIGIN OF THE INVENTION This invention was made under Contract No. DE-AC07-94ID13223, Contract No. DE-AC07-99ID13727, and DE-AC07-05ID14517 awarded by the United States Department of Energy. The government has certain rights in the invention.