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Apparatus and method for tracking a molecule or particle in three dimensions

United States Patent

March 3, 2009
View the Complete Patent at the US Patent & Trademark Office
Los Alamos National Laboratory - Visit the Technology Transfer Division Website
An apparatus and method were used to track the movement of fluorescent particles in three dimensions. Control software was used with the apparatus to implement a tracking algorithm for tracking the motion of the individual particles in glycerol/water mixtures. Monte Carlo simulations suggest that the tracking algorithms in combination with the apparatus may be used for tracking the motion of single fluorescent or fluorescently labeled biomolecules in three dimensions.
Werner; James H. (Los Alamos, NM), Goodwin; Peter M. (Los Alamos, NM), Lessard; Guillaume (Santa Fe, NM)
Los Alamos National Security, LLC (Los Alamos, NM)
11/ 544,988
October 6, 2006
STATEMENT REGARDING FEDERAL RIGHTS This invention was made with government support under Contract No. DE-AC52-06NA-25396 awarded by the U.S. Department of Energy. The government has certain rights in the invention.