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CBH1 homologs and variant CBH1 cellulases

United States Patent

7,452,707
November 18, 2008
View the Complete Patent at the US Patent & Trademark Office
National Renewable Energy Laboratory - Visit the NREL Technology Transfer Website
Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.
Goedegebuur; Frits (Rozenlaan, NL), Gualfetti; Peter (San Francisco, CA), Mitchinson; Colin (Half Moon Bay, CA), Neefe; Paulien (Zoetermeer, NL)
Danisco A/S, Genencor Division (Palo Alto, CA)
10/ 804,785
March 19, 2004
STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT Portions of this work were funded by Subcontract No. ZCO-0-30017-01 with the National Renewable Energy Laboratory under Prime Contract No. DE-AC36-99GO10337 with the U.S. Department of Energy. Accordingly, the United States Government may have certain rights in this invention.