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Method of identifying hairpin DNA probes by partial fold analysis

United States Patent

October 28, 2008
View the Complete Patent at the US Patent & Trademark Office
Methods of identifying molecular beacons in which a secondary structure prediction algorithm is employed to identify oligonucleotide sequences within a target gene having the requisite hairpin structure. Isolated oligonucleotides, molecular beacons prepared from those oligonucleotides, and their use are also disclosed.
Miller; Benjamin L. (Penfield, NY), Strohsahl; Christopher M. (Saugerties, NY)
University of Rochester (Rochester, NY)
11/ 553,904
October 27, 2006
This invention was made, at least in part, with funding received from the U.S. Department of Energy under grant DE-FG02-02ER63410.000. The U.S. government may retain certain rights in this invention.