Skip to Content
Find More Like This
Return to Search

Dual fiber microprobe for mapping elemental distributions in biological cells

United States Patent

July 31, 2007
View the Complete Patent at the US Patent & Trademark Office
Oak Ridge National Laboratory - Visit the Partnerships Directorate Website
Laser-induced breakdown spectroscopy (LIBS) is applied on a microscale for in situ elemental analysis and spatial mapping in biological cells. A high power laser beam is focused onto a cell surface using a dual branching optical fiber probe for optical excitation of the cell constituents. Dual spectrometers and ICCD detectors capture the emission spectra from the excited cell(s). Repeated probing or repositioning of the laser beam with respect to the cell can provide 2-D or 3-D mapping of the cell.
Martin; Rodger C. (Powell, TN), Martin; Madhavi Z. (Powell, TN)
UT-Battelle, LLC (Oak Ridge, TN)
11/ 240,264
September 30, 2005
RESEARCH OR DEVELOPMENT The United States Government has rights in this invention pursuant to Contract No. DE-AC05-00OR22725 between the United States Department of Energy and UT-Battelle, LLC.